VIDEO: Highlights of Denver Broncos 10-6 Win Over San Francisco 49ers

LIVE: Denver Broncos Take on San Francisco 49ers — Twitter Updates

The Denver Broncos will take on the San Francisco 49ers at 7 p.m. (MT) tonight on  KTVD Channel 5 (20).  Out of town fans can watch the game on NFL.com's Preseason Live package.

KTVD's Kevin Burkhardt (play-by-play) and John Lynch (color commentary) will be calling the game and Rod Macke will be reporting on the sidelines at Candlestick Park.

Last season, the Broncos finished 13-3 in regular season play while the 49ers went 11-4-1.  Denver's season ended when they fell to the Ravens in the divisional round of the playoffs. Three weeks later, San Francisco fell to the same Ravens in the Super Bowl.

Entering the 2013 season, the Broncos and 49ers are considered among the top teams in the NFL.  Tonight's game—or at least the first half—could be a preview of this season's Super Bowl.

Follow along live after the jump with some of our favorite game day Tweeters:

With Offensive Line Ailing, Should Peyton Manning Even Play Tonight?

For the starters, preseason games are meaningless.

Sure, preseason matches allow you to fine tune things and get on the same page with your new quarterback (here's looking at you, Wes Welker), but in Week 1, the starters only play the first quarter—if that.

So with Denver's offensive line banged up, should the Broncos even risk playing quarterback Peyton Manning tonight against the San Francisco 49ers?  The last thing Denver's staff wants to see is San Francisco's Aldon Smith blindsiding their $17.5 million quarterback in a meaningless exhibition game.

It's a subject up for debate, but the fact is, Manning may have to play with this patch-work offensive line during the regular season if any of the o-linemen have reoccurring injuries.  The time is now for Manning to get on the same page with his line.

"Certainly, you think about it because you’ve got good offensive players, so if they’re injured and not in there, then it does make an impact on your team,"  Manning said after practice on Tuesday when asked if he was concerned about the injuries suffered along Denver's offensive line this summer.